The antibacterial drug abuse blocking action is fired
A few days ago, Ministry of Public Health released in succession>With " antibacterial medicine clinical practice special renovation activity scheme in the whole country of 2011 years ". A 3 - year long national antibacterial medicine clinical practice special administration has raised the curtain formally.
The chief pharmacy expert, hospital of Ministry of Public Health of Ministry of Public Health manage the medicine thing of research institute and manage Wu YongPei, director of research department, to tell reporters, the phenomenon against drug abuse of fungus of our country is very serious, wide in variety, the consumption is large, the ones that cause able to bear medicine " The super bacterium " Increase, if things go on like this, face not having usable awkward situation of medicine. This question has already aroused great concern from many departments such as Ministry of Public Health, this special renovation activity has been regarded as " medical Long March to Quality Campaign " With " satisfied " The important content of the activity, it will renovate the result and will be regarded as the president and chief of the office of department and promoted the important index of appraising and choosing excellent.
The variety consumption of antimicrobial is limited
"The one most difficult to reach to renovate in the standard is to bring the antibacterial medicine variety down to under 50 kinds, need fully communicating with the director of each clinical department, do the work of selecting well together. " The head of the department of medicine of hospital of a the first, second and third tells reporters, there are more than one hundred kinds of product rules against fungus medicine of the hospital at present, whether select someone very difficult choice.
The draft proposes, the antibacterial medicine variety of tertiary hospital does not exceed 50 kinds in principle, second hospital antibacterial medicine variety does not exceed 35 kinds in principle. The same common name injects dosage form and oral dosage form and does not exceed 2 kinds respectively, the prescription makes up compound preparation that is similiar to from 1 kind to 2 kinds; Three generations and four hair spore fungus plain ' Includes compound preparation) Oral dosage form of one kind of antibacterial medicines does not exceed 5 product rules, it doesn't exceed 8 product rules to inject dosage forms, carbon blue and green mould alkene antibacterial medicine inject dosage form, exceed 3 the intersection of product and rule, the intersection of Fluorine and the intersection of quinoline and the intersection of promise and ketone antibacterial the intersection of medicine and oral dosage form and inject dosage forms, respectively less than 4 product rules, the deep department does not exceed 5 product rules resisting the fungi type antibacterial medicine.
Wu Yong wears the introduction, according to the finding of Ministry of Public Health, the antibacterial medicine which the medical organization of our country uses has between 150 kinds and 160 kinds at present, but some variety that has eliminate for a long time abroad, accord with safe effective economic medicine, select principle at all.
It is reported, there is quinoline promise ketone antimicrobial now in our country 18 kinds, and a lot of countries can meet the clinical need when only having 6 kinds. �� - inner amide enzyme inhibitor is very confused too, Wu YongPei says, a lot of enzyme-added inhibitors are all nonsensical in this kind of medicines, all imagine, lack the scientific experimentation basis according to researcher. The patient not only will cause poisonous side reaction if the patient uses such a medicine, but also it is able to bear the medicine incidence to increase.
While limiting the variety, the more important thing is the control of consumption. As to this, the draft proposes, the medical organization is in hospital patient's antibacterial medicine rate of utilization does not exceed 60%, the prescription proportion of antibacterial medicine of clinic patient does not exceed 20%, the intensity of antibacterial drug use strives to control below 40DDD.
DDD is that the adult limits the unit of measurement of the dosage on day, can pack dosage and various the intersection of medicine and daily the intersection of dosage and different influence, reflect using frequentness of the medicine, the intersection of medicines and selling price. Wu wears explaining, according to World Health Organization (WHO) forever To the regulation of the dosage of day of each kind of medicine, taking the medicine once according to the regulation is one DDD, it is DDD the higher, it is the worse to explain the rationality of using medicine. The requirement for 40DDD of our country refers to every hundred people's antibacterial drug use frequentness of every day, this is a standard of WHO too. It is reported, the antibacterial medicine of hospital of our country uses frequentness to reach 81DDD equally now, reach the goal and still have very great disparity.
After there are clear regulations on DDD, will lead the medical organization to choose to use advanced antibiotic? He explains, only limits DDD, it is really a shortcut to do it in this way. But proportion of Ministry of Public Health to total amount of money of medicines to the antibacterial medicine has a requirement, pass " combination blow " To avoid this trend.
The antibacterial treatment " The medicine route " It is expected to issue
Before the draft is issued, the relevant department opposes the unreasonable concrete links that used of fungus medicine to investigate. Finding finds, the unreasonable phenomenon in preventing from using medicine of antibacterial medicine is the most common. For example the one that can not need the antibacterial medicine in I notch has been used, some patients used the antibacterial medicine in more than 2 hours before operation, have already lost and prevented the result at the time of the operation.
In order to standardize using the antibacterial medicine, has made the corresponding quantized regulation to this too in the new rule. Is notch operation patient prevents from using the antibacterial medicine proportion not to exceed 30%; Patient's surgery prevents from using the time of antibacterial medicine to control between 30 minutes and 2 hours before the skill in hospital; Is notch operation patient prevents from using the time of antibacterial medicine to less than 24 hours.
Wu YongPei says, the abuse against fungus medicine not merely means big consumption, select an unreasonable a kind of form of expression that abuses too of medicine. He finds in a lot of hospitals, can use the thiazole forest of ordinary dosage form very beginning spore, clinic often uses anhydrous preparation for the patient, the result does not have obvious difference, but the expenses are much more expensive. The relevant department makes between 1 kind and 2 kinds of technical specifications against drug use of fungus in consideration too, similar to the clinical route. But he says frankly, " medicine route " More complicated, indication is not very clear, medicines that can be chosen are many too, how does the norm still needs the discussion.
He especially emphasizes, the doctor has clear purpose while using the antibacterial medicine, can't replace the cleaning before and after operation with the antibacterial medicine, let alone replaced the infection operated in operation to control.
Have also proposed setting up the hierarchical management system of antibacterial medicine in the new rule, divide the antibacterial medicine into exercising restraint in using, exercising restraint in using and using specially tertiarily. Soliciting the opinion, will issue in the near future too in antibacterial medicine differentiated control catalogue.
The new rule initiates the medicine enterprise of the hospital to move
The first affiliated hospital medicine head of the department Ma ManLing in Harbin medical university says when being interviewed by reporter, there are antibacterial medicines about about 100 kinds in the hospital now, cut down nearly half according to the fixed need. The hospital is putting emphasis on using medicine rationally mainly at present, the selection of the variety has not begun formally yet. "The foreign hospital is antibacterial the medicine is less than 50 kinds, enough all the same too, 800 kinds can have living space in even if our hospital, the more important thing is to see the renovation efforts of the government " . Lu of Beijing Tong Zhou District the intersection of river and the intersection of hospital and Chen ShiCai, head of the department of medicine, show too, though the work that the prescription commented on has been done, but a lot of of the antibacterial medicine treat the principle and has not still totally implemented, this renovation is to strengthen the normal good chance.
In one website which the clinical pharmacist relatively gathered, the special renovation of antibacterial medicine is the topic discussed warmly recently, a lot of net friends hope this renovation can be strengthened, turn back the current situation.
ManLing Ma think draft and renovate scheme, it makes regulations that quantizes to be very essential to a lot of index, the goal in execution of medical organization is clearer. But reflect clinically, plant the pace maker into and is there is " recessiveness is infected " in the brain department's operation Question,this even if pieces of problem is at operation been aseptic exist too. If antibacterial drug use can not reach 3 hours, may make the operation fail, even have a life danger. In they are collecting the materials in this respect too.
The preparation of the hospital " In full preparation" ,But enterprises are not so steady.
One sales manager of foreign enterprise that one are responsible for the market of Beijing says with feeling, the company has a meeting everyday recently, assign the counter-measure of this special renovation. According to his introduction, the company has already greeted with every medical representative, if their responsible medicine has been " taken down " by the hospital ,Ask them to resign automatically. Executive this think special renovation disaster and happiness rest on for company, if oneself operation succeed in, market share will increase instead.
A person in charge of pharmacy enterprise specializing in producing antibiotic in Jiangxi says, they had already paid close attention to the differentiated control of antibacterial medicine long ago. This that as for the restriction of the variety, he thinks " instead of it is a competition among variety, enterprise, it is a competition among agent's background to not so good as saying " . " taken down " Probably mostly domestic medicines.
In worry of unfavorable status as to the domestic antibacterial medicine, Ma ManLing has expressed her view in terms of professional personnel of pharmacy. She thinks, according to clinical result of use, really there are advantages in the medicines in the foreign enterprise, and more obvious. Removing the interests to drive, the doctor sets out from patient's security and therapeutic effect, also like to choose their products, the patient that the economic condition is better has such a demand. It seems, except state-owned enterprise practises the channel, must practise the exercises to benefit the internal organs.
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